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Based on the data in children and adolescents and the clinical experience of experts, aprepitant is currently recommended as an alternative prophylactic treatment in patients that do not respond to or do not tolerate standard therapy with amitriptyline or topiramate

Glaesner W, Vick AM, Millican R et al (2010) Engineering and characterization of the long-acting glucagon-like peptide-1 analogue LY2189265, an Fc fusion protein