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One of the reasons of this paradox is the large number of reports stating that brain atrophy and degeneration of nerve cells, observed with dementia, can occur without cerebrovascular pathology, but only through the amyloid fault, leading to the struggle with amyloids, and not with the causes that gave birth to them, and made the AD a permanently incurable disease with unknown etiology

Colchicine for prevention of postpericardiotomy syndrome and postoperative atrial fibrillation: the COPPS-2 randomized clinical trial

Cortisol suppresses Bmal1 gene transcription by promoting Cry expression, thereby regulating its own circadian peak (50)

Early intervention with probiotics and metformin alleviates liver injury in NAFLD rats via targeting gut microbiota dysbiosis and p-AKT/mTOR/LC-3II pathways