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Temperature Fluctuations: Leaving the vial out for extended periods or storing it in a fridge with poor temperature control can weaken the preservative's efficacy

However, the inhibitory effect of NPW on MPO activity and NPW-induced increase in GSH content were not observed when NPW injections were preceded with either the selective COX-1 inhibitor ketorolac or the non-selective COX-inhibitor indomethacin, but the effects of NPW were not altered by the COX-2 inhibitor NS-398

Camargos CH, Yang L, Jackson JC, Tanganini IC, Francisco KR, Ceccato-Antonini SR, Camargos CHM, Rezende CA, Faria AF (2025) Lignin and nanolignin: next-generation sustainable materials for water treatment