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The main efficacy outcome measures in the KEYNOTE-177 trial were progression-free survival (PFS) and overall survival (OS), with median PFS demonstrated to be 16.5 months (95% confidence interval [CI], 5.4, 32.4) in the pembrolizumab arm and 8.2 months in the chemotherapy arm (95% CI, 6.1, 10.2)

Moreover, other important chondrocyte-specific proteins, such as Cartilage Oligomeric Matrix Protein, Aggrecan and Cartilage-associated Protein, are produced and secreted at significant levels by chondrocytes at P6

The substance chosen to fill in this space may vary depending on your discussion with our team and your personal goals

Its main effects are already well-understood, and that opens the door to multi-peptide study designs