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Substantial differences across all studies include the use of different biomarkers to characterise B 12 status, different tests/cut-offs to assess depression, different follow-up time periods, different confounders in statistical modelling and different food fortification or B 12 supplement use/guidelines in the various international populations

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Use consistently, especially in areas prone to friction and trauma

To benefit from astaxanthins antioxidant properties, consider eating salmon once or twice a week