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B12 is safe on its own, but a few conditions call for extra care, which is why a provider reviews your history before treatment: Leber's hereditary optic neuropathy, a rare inherited eye condition, where certain forms of B12 may be a concern for the optic nerve

B12 shots are safe for most people, but those with certain health conditions should consult a doctor before starting treatment

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It is required for the metabolism and transport of fats and cholesterol from the body, which is also important for the healthy support of the endocrine, cardiovascular and hepatic systems