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Drugs and Biologicals with Average Annual Total Cost Under Part D Below the Applicable Threshold Under section 1860D-14B(g)(1)(B) of the Act, a drug or biological is excluded from the definition of a Part D rebatable drug if the average annual total cost under Part D for such period per individual who uses such a drug or biological product is less than $100 per year, as determined by the Secretary using the most recent data available, or, if data are not available, as estimated by the Secretary

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Thiamine works as a co-enzyme for complexes including enzymes essential for intracellular glucose metabolism, such as transketolase, pyruvate dehydrogenase (PDH), and -ketoglutarate dehydrogenase