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The relationship between structural and functional connectivity is altered in PD, with less close coupling, particularly in PD patients at higher risk of dementia 152 and those with visual hallucinations 239

Muckenthaler MU, Galy B, Hentze MW.Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network.Annu Rev Nutr

Without enough B12, you may feel weak, tired, or forgetful, and it can affect your overall health

Vitamin B12 treatment increases serum B12 concentrations and decreases methylmalonic acid and homocysteine levels [18], but the normalization of these markers does not always correspond to clinical improvement