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Preclinical Research Findings The published 5-amino-1MQ dataset comes primarily from mouse models of diet-induced obesity: In vitro studies demonstrated NNMT inhibition in differentiated adipocytes, with reduced 1-methylnicotinamide and increased NAD+ at micromolar concentrations

One key group includes individuals with pernicious anemia, an autoimmune condition that affects the bodys ability to absorb vitamin B12 from food