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2002 Mar;133(3):274-6

When to reassess If GI symptoms worsen instead of improving over the first 2-3 weeks of a step, if dysesthesia appears suddenly, or if you cannot keep food down, pause and consult a qualified clinician

On the other hand, there is evidence that spinal cord injury triggers a cascade of secondary degenerative events that cause further damage to the injured area and induce local inflammation along with hemorrhage and edema [12, 13] and that the therapeutic agents imatinib (which has been shown to inhibit cytokine production and reduce hemorrhage, edema, and inflammation) [14] and ibuprofen initiate favorable axonal growth and functional recovery through Rho inhibition [15]

The anastomoses were also weakened, resulting in water loss in the body and subsequently weight loss