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This increase in ECM proteins fibrosis separates the individual bundles of muscle cells and disturbs the impulse propagation that causes the heart to beat regularly.[ref] Animal studies from about a decade ago show a pressure overload in the heart (stressing out the heart) can cause mast cells to proliferate

Cycle Length Typically 4-12 weeks depending on injury severity and treatment goals

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Tavares H, Oliveira M, Costa R, Amorim H (2022) Botulinum toxin type A injection in the treatment of postparetic facial synkinesis: an integrative review