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Promising OS and PFS data have been shown, especially in non-squamous taxane-nave NSCLC (n=42), with a median PFS of 6.4 months (95% CI, 4.5 to 10.5) and median OS of 16.3 months (95% CI, 11.5 to NR), compared to 3.5 months (95% CI, 2.7 to 5.3) and 11.2 months (95% CI, 8.3 to 13.7), respectively, in all NSCLC subtypes [87]

GENEROSO, W.M., CAIN, K.T., KRISHNA, M., SHEN, C.W., & GRYDER, R.M

Because it plays such a central role in protecting cells from oxidative stressthe internal wear and tear caused by free radicalsit is often referred to as the body's master antioxidant

128 The multi-subunit NADH-ubiquinone oxidoreductase (complex I) is the first enzyme complex in the mitochondrial electron transport chain (ETC)