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As the follicle moves toward catagen and telogen, DPC activity decreases

Graf and Kastin proposed in their 1984 review that DSIP exerts programming rather than acute pharmacological effects a framing that captures the reproducibility difficulties of the literature

Elimova E, Wang X, Qiao W, Sudo K, Wadhwa R, Shiozaki H, Shimodaira Y, Planjery V, Charalampakis N, Lee JH, Weston BR, Bhutani MS, Komaki R, Rice DC, Swisher SG , Blum MA, Rogers JE, Skinner HD, Maru DM, Hofstetter WL, Ajani JA