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The relatively slower growth rate and lower growth yield of the wild-type and ghd3 / gdh3 strains on proline or arginine medium, compared to MM medium, can be explained by the fact that amino acids are poor carbon and nitrogen sources in comparison to the glucose and ammonia present in MM medium

Interestingly, type I IFN targets also human neutrophils, for instance by prolonging their survival 16 , or by inducing the expression of CXCL10 mRNA 17 and the production of biologically active TNF-related apoptosis-inducing ligand (TRAIL) 18

This approach allows us to move beyond a one-molecule-one-target framework and instead map the complex interaction network through which TCM components modulate the genome, transcriptome, and proteome, thus revealing the multi-level regulatory landscape of TCM

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