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The findings were also reflected in a decreased co-localization of mitotracker and lysotracker following treatment with 3-methyl adanine and increased co-localization of mitotracker and lysotracker by rapamycin treatment (Taki et al., 2020)

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Cytochrome P450 monooxygenase also alters therapeutic responses by inactivating antitumor agents, leading to the development of chemotherapy resistance [180]