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Figure 8: Cancer cells produce GGT, depleting glutathione and increasing ROS, which damages cells and disrupts metabolism

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Although THC possesses neuroprotective antioxidant properties through non-CB1R pathways [33], it also upregulates plasma inflammatory cytokines [34], increases vulnerability to ischemic stroke in young people [35], increases mitochondrial dysfunction [36, 37] and alters gene pathways associated with mitochondrial oxidative phosphorylation [38]

Inflammatory and oxidative stress markers in post-traumatic stress disorder: a systematic review and meta-analysis