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Nowadays we experience abundant high-calorie processed foods available year-round, but reduced physical activity due to cold weather, and mood-driven eating triggered by seasonal changes

The increase of ROS within a high oxidative stress level (by decreasing of the antioxidant GPx enzyme) increases the possibility of lipid oxidation, especially LDL-cholesterol and thus favors the formation of anti-LDL-oxidized cholesterol antibodies, which will lead to the initiation of an immune and vascular aggression process (13-18)