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Oral B12 is usually taken daily at 1,000 to 2,000 mcg

Adverse Reactions/Side Effects Side effects observed in association with the use of triamterene and hydrochlorothiazide tablets, other combination products containing triamterene/hydrochlorothiazide, and products containing triamterene or hydrochlorothiazide include the following: Gastrointestinal: jaundice (intrahepatic cholestatic jaundice), pancreatitis, nausea, appetite disturbance, taste alteration, vomiting, diarrhea, constipation, anorexia, gastric irritation, cramping

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Ethics approval for animal experimentation was obtained from Washington State University