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GregoryJCBuffaJAOrgEWangZLevisonBSZhuWet al

Indeed, NMDAR-dependent calcium influx triggers nNOS to generate NO thereby compounding the effects of SNO-Src and SNO-SHP-2 and further contributing to NMDAR-mediated excitotoxicity

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According to their review, the clinical characteristics of other PAIS appear almost indistinguishable from long COVID as described above, including exertion intolerance, fatigue, neurocognitive and sensory impairment, sleep disturbances, joint and muscle pain, and non-specific symptoms that are often present but of variable severity