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Dietary compounds such as choline, carnitine, and betainefound in red meat, eggs, and some supplementsare metabolized by gut microbiota into trimethylamine (TMA)

In endothelial cells (ECs), overexpressed CPTI can promote cancer growth through acceleration of tumor neovascularization

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In patient 3, the normalization of plasma L-carnitine levels was accompanied by improvement of muscle weakness and fatigability, while the degree of -BB accumulation in the plasma remained unchanged upon L-carnitine supplementation