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In animal models of Parkinsons disease and Alzheimers, MTP-131 has shown potential in preventing neuronal death, improving synaptic plasticity, and enhancing neurogenesis

Yet, the short duration of the study did not permit a conclusion on whether the lowering of homocysteine through B-vitamin supplementation could have long-term benefits on bone strength and fracture risk (119)

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The abnormal vasculature disrupts the delivery and distribution of drugs, thereby preventing effective drug concentrations from being achieved within tumors and leading to drug resistance