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As a consequence, they encountered increased pain and swelling, requiring additional medical attention and a lengthened recovery period

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The disappointment was magnified by expectation

It was hypothesized that the acquisition of a procoagulant phenotype by medulloblastomafavors its dissemination because the enrichment of the tumor environment with fibrin protects the cancer cells from the immune system and forms a matrix for cell migration (Provencal et al., 2009)