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Circulation 99:29342941 Anselmi A, Abbate A, Girola F, Nasso G, Biondi-Zoccai GG, Possati G, Gaudino M (2004) Myocardial ischemia, stunning, inflammation, and apoptosis during cardiac surgery: a review of evidence

Table 5.4: Common adverse events of the four PDE5Is currently EMA-approved to treat ED* * Adapted from EMA statements on product characteristics

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The aberrant SNO of the mitochondrial proteins is likely to lead to mitochondrial dysfunction and contribute to ASD pathogenesis