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P = 3.41e-03), Ile (OR, 1.06

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for example, administration of AS-IV at 0.3 and 1.0 mg/kg/day improved cardiac function in a rat model of heart failure (Zhao et al., 2009)

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It is produced by plants and most microorganisms from prephenate, an intermediate on the shikimate pathway

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Orellana LH, Ben Francis T, Ferraro M, Hehemann JH, Fuchs BM

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