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Bibcode:2011ToxAP.253..197A

A qualified nurse or healthcare professional will need to access a vein and secure the needle in place, which could take a couple of attempts if the patient is dehydrated

Amino Acids 45 , 133142 (2013)

Most studies on the paracellular route of transport describe at least two populations of pores regulated by TJs: (1) a high capacity charge selective pore permeable to small ions and small uncharged molecules (referred to as the pore pathway), and (2) a much larger low-capacity pore (commonly referred to as the leak pathway) permeable to large ions and molecules irrespective of charge