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Another strategy employs multifunctional nanoassemblies, PC@GCpD(Gd), which incorporate polydopamine-stabilized graphene quantum dot photosensitizers, CpG oligodeoxynucleotide-based immune adjuvants, and Gd/Cy3 imaging probes for dual photothermal and photodynamic tumor eradication and immune activation through TLR9-mediated cytokine release and DC maturation, resulting in nearly complete suppression of EMT6 tumors with real-time MR and fluorescence imaging guidance [63]

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