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Parkin, an E3 ubiquitin ligase whose mutations are the most common cause of hereditary Parkinsons disease (PD), is less persulfurated in the PD brain than in the normal brain 13, 35

The ground seeds were defatted with hexane for 6 h using the Soxhlet method (1:10) and then placed in trays at room temperature for 12 h to eliminate the excess solvent (Reference Arce-Ortiz, Jimnez-Martnez and Gutirrez-Rebolledo9)