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The T9 and T11 vertebral plates of the rats were subsequently clamped, and the rats were placed on a spinal cord percussion device (Precision Systems and Instrumentation IH Spinal Cord Percussion Device, USA) with the percussion force set to 250 kdynes, resulting in a moderate SCI model

Phase II Liver Detoxification Pathway Phase II liver detoxification neutralizes the byproducts of Phase I liver detoxification and other remaining toxins

Once Nrf2 is activated, the storage of iron would increase, OS would be inhibited, and the occurrence of ferroptosis could be directly blocked

281 Melatonin inhibits the stress effect of ER through the melatonin receptors type 1B (MT2)/cAMP/protein kinase A (PKA)/inositol-requiring enzyme 1 (IRE1) pathway, reducing hepatic ferroptosis in MAFLD