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While powerful tools for non-invasive, longitudinal, in vivo assessment, MRI, DTI, and MTR do not allow for microscopic assessment and can be confounded by edema, although this issue is not a particular consideration for the cuprizone model given that vasogenic edema does not play a prominent role

LC-MS Methods The liquid chromatographymass spectrometry (LC-MS) is overall used in food analysis because of its versatility, specificity, and selectivity

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