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The inhibitor effect is concentration dependent

2.2.3 DHODH pathway Dihydroorotate dehydrogenase (DHODH) is a mitochondrial inner membrane enzyme that plays a role in important metabolic pathways such as cytochrome P450, purine synthesis, and fatty acid metabolism (75, 76)

If, however, that man weighed 50 pounds more, it would take six standard drinks over one hour to reach a BAC of .08, or eight standard drinks over three hours