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Besides the acute phase gastrointestinal effects which may lead to up to 10% of people discontinuing the drugs, there are other potential GI side effects of obstruction, excessive loss of muscle mass, and potentially association with some eye disease adverse events

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Based on the information provided in the comment, we agree with the applicant that all components of the aprevo Cervical ACDF System, including the aprevo insertion instrument, integrated fixation screws, and CAM, are integral parts of the service furnished