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Upon activation, these cells undergo a metabolic shift toward anabolism, increasing glycolysis to meet the demands of rapid proliferation

Quantitative structureactivity relationship (QSAR) studies Traditional QSAR-based methods are very common in early drug design and prior to discovering new lead compounds or for use in drug repurposing to predict the relationships between the structural properties of chemical compounds and biological activities, thus helping in ligand-based drug design [27]

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[DOI] [PubMed] [Google Scholar] 58.Adan R.A., van der Beek E.M., Buitelaar J.K., Cryan J.F., Hebebrand J., Higgs S., Schellekens H., Dickson S.L