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doi: 10.1101/cshperspect.a022277 76 Ansa-AddoEAZhangYYangYHusseyGSHowleyBVSalemMet al

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10.1002/ana.24066 117 RegoA

Typically the serum bicarbonate concentration will be 16 mmol/L) indicates the presence of excess 'unmeasured' anions, such as lactic acid in anaerobic metabolism resulting from tissue hypoxia, glycolic and formic acid produced by the metabolism of toxic alcohols, ketoacids produced when acetyl-CoA undergoes ketogenesis rather than entering the tricarboxylic (Krebs) cycle, and failure of renal excretion of products of metabolism such as sulphates and phosphates