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Use of blood flow restriction therapy with low intensity exercise allows lower knee joint pain in comparison to high intensity training without blood flow restriction

ACN ice-cold acetonitrile Rats Male Sprague-Dawley rats (250+ g) were allowed food (Harlan Teklad rodent diet) and water ad libitum in our AAALAC certified animal facility

Cell transfection Cells were transfected with pcDNA 3.1 overexpression vectors (pcDNA 3.1-YTHDF1 and pcDNA 3.1-SLC7A5, with the empty pcDNA 3.1 vector as a negative control) and siRNAs (Invitrogen) targeting YTHDF1 and SLC7A5 (si-YTHDF1, si-SLC7A5, with non-targeting siRNA (si-NC) as a negative control)

Donorrecipient mismatch in FMT and poor colonization of many probiotic strains limit durable effect [274, 275, 321]