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We came to realize that trying to treat celiac disease may be a tall order because of the very high sensitivity of celiac patients to these gluten peptides, she said

It was proposed that hypoxia activates transcription via a mitochondria-dependent signaling process involving increased ROS, whereas CoCl 2 activates transcription by stimulating ROS generation via a mitochondria-independent mechanism [7274]

Conclusion: While initial findings are promising, further research is required to validate the clinical efficacy of these protective agents