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The report of the fast antidepressant effects of KET, a non-selective glutamate agent, fostered interest in the role of glutamate in specific neurological functions (Henter et al., 2017

R.KnyazevY

10.1091/mbc.e08-12-1248 Mol

21,22 In one case, a 15-year-old male on valproic acid with a history of migraines, ADD, learning and behavioral problems acutely developed hyperammonemia and fatal cerebral edema OTC deficiency was diagnosed at autopsy