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A 2025 pilot IV study (1020mg, n=2) showed no adverse effects on biomarkers

TRPs depolarize excitable cells by increasing the influx of Ca 2+ , Na + , and other cations

16,17 In certain instances, these D 2 -like receptor variants may possess divergent abilities to couple to or activate G proteins, 18,19 and can also display differing pharmacological properties