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Among them, cysteine S-nitrosylation and tyrosine nitration are prominent indicators of nitrosative stress, reflecting a direct interplay between redox control and protein function

A double-blind RCT showed that YWXY improved the Operative Link on GastricIntestinal Metaplasia Assessment (OLGIM) stage, relieved symptoms of atrophic gastritis induced by H

This lack of efficacy may be attributed to the low plasma and sputum concentrations of NTZ and the high plasma protein binding of tizoxanide, the active metabolite of NTZ [80], highlighting the need for further pharmacokinetic optimization and clinical research to better understand its potential role in TB treatment