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Description

Based on preclinical data demonstrating substantial MPNST shrinkage in mice treated with a combination of MEK and mTOR inhibitors, SARC031 is a trial of the MEK inhibitor selumetinib in combination with the mTOR inhibitor sirolimus for patients with unresectable or metastatic MPNST

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[48] Perfringolysin O [edit] Perfringolysin O (PFO) is a pore-forming haemolytic toxin belonging to the cholesterol-dependent cytolysin (CDC) family

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