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Specifically, either a testosterone patch providing 300 mcg of testosterone per day or a cream or gel providing 5 mg of testosterone per day is generally effective at restoring free testosterone levels to the normal premenopausal range

Shariat A, Noormohammadpour P, Memari AH, Ansari NN, Cleland JA, Kordi R

doi: 10.6000/1927-7229.2014.03.02.2

In one placebo-controlled study with 75 ulcerative colitis patients, 100 mg saffron daily for eight weeks improved clinical activity index scores, total antioxidant capacity, and increased levels of the antioxidant enzymes superoxide dismutase and glutathione peroxidase compared with placebo (Tahvilian 2021)