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All participants were counseled on lifestyle modification, including a daily 500-kcal calorie deficit and at least 150 minutes of physical activity per week

We use methylcobalamin, the active, highly bioavailable form of vitamin B12, so your body can use it efficiently at the cellular level

SAEs relatedness to the administration of vitamin B 12 or placebo will be judged by the investigator/designee, the Ethics Committee and the DSMB who will have access to all relevant investigations, clinical assessments and if require unblinding allocated interventions

That basically means no one knows whether the vitamin helps or hurts, or even if deficiencies increase your risk