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Bioavailability and Conversion: Methylcobalamin is the active form of vitamin B12, meaning it does not require conversion by the body to be utilized

[10] Long-term use of proton pump inhibitors (PPIs) and H2-receptor antagonists reduces gastric acid, potentially impairing the release of B12 from dietary proteins

Does Vitamin B12 really make you gain weight, or is it just a misunderstanding

This article explains what each treatment involves, how they are sometimes used together, the current evidence base, and the important safety and regulatory considerations every patient should understand before seeking either therapy