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Therefore, the severe interstitial edema, more expressed in white than in gray mater, and severe neuron loss in hippocampal neurons, neurons of dentate nucleus, Purkinje cells and other cerebellar nuclei and less severe damage in the pons, the mesencephalon and lateral geniculate body could be a specific paracetamol effect and these territories could be involved in the occurrence of maximal paracetamol induced seizures

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Add each solvent one by one: PBS Solubility: 33.33 mg/mL (74.63 mM)

Thus, the phosphorylation leads to the dissociation of the IkB-p65/p50 complex, resulting in the proteasomal degradation of IkB and the subsequent translocation of the p65-p50 heterodimer to the nucleus