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Both pump systems are ATP-dependent and are inhibited by vanadate but differ in that P-glycoprotein appears to have specificity towards hydrophobic compounds whereas the glutathione S-conjugate carrier is as its name suggests specific for leukotrienes and drug-glutathione conjugates

Protein engineering of oxidoreductases utilizing nicotinamide-based coenzymes, with applications in synthetic biology

Cytokine storm of graft-versus-host disease: a critical effector role for interleukin-1

Gao Y, Van Haren MJ, Buijs N, Innocenti P, Zhang Y, Sartini D, Campagna R, Emanuelli M, Parsons RB, Jespers W (2021b) Potent inhibition of nicotinamide N-methyltransferase by alkene-linked bisubstrate mimics bearing electron deficient aromatics