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[DOI] [PubMed] [Google Scholar] 416.Ramsahai J.M., Hansbro P.M., Wark P.A.B

Timing optimization (morning fasted-state dosing) does not change the compounds safety profile

Here, precision-cut liver slices (PCLiS), primary human hepatocytes (PHH), primary rat hepatocytes (PRH), and HepG2 cells with rat or hamster S9-mix were investigated as in vitro model systems