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Furthermore, a pre-clinical study showed that an FXR agonist regulates genes involved in antimicrobial defence and immune modulation, such as the genes encoding angiogenin-1 (Ang1) and inducible nitric oxide synthase, in the ileum [57]

( B ) PreBAT total AR OD by image analysis among nonresponders (NR) and responders (R) with median indicated by line ( n = 24)

[DOI] [PubMed] [Google Scholar] 102.Campbell C.M., Kipnes M.S., Stouch B.C., Brady K.L., Kelly M., Schmidt W.K., Petersen K.L., Rowbotham M.C., Campbell J.N