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Artesunate inhibits TGF-1-induced epithelial-to-mesenchymal differentiation (EMT) and RLE-6TN cell proliferation by upregulating Smad7 mRNA and protein expressions and downregulating Smad3, ACTA2, and Vim mRNA expressions (Wang et al., 2014)

For Lyme disease and cancer specifically, the oxidative stress driving cellular damage can be directly counteracted at these concentrations in ways that feel more like supporting the body's own defenses than imposing a foreign treatment

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8 Genetic mechanisms of alopecia areata The likelihood of developing AA has been associated with a positive family history in several studies