glutathione synthesis rate-limiting step Glutathione Biochemistry | Glutathione Synthesis

A comparison with the structure of glutathione reductase

Normally, almost all glutathione in the mitochondria is reduced glutathione, but in the presence of mitochondrial dysfunction, the proportion of oxidised glutathione increases due to the increased elimination of ROS

Hepatology 69, 17681786.CrossRefGoogle ScholarPubMed Lee, H-M, Kim, J-J, Kim, HJ, Shong, M, Ku, BJ, and Jo, E-K (2013) Upregulated NLRP3 inflammasome activation in patients with type 2 diabetes

[10] Imaging [10] MRI abdomen (without contrast) Used to estimate hepatic iron concentration (HIC) Hepatic iron pattern can help to distinguish between hereditary hemochromatosis and secondary iron overload