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In addition, ggplot2 was employed to show the relationship between CAV2 expression and clinical outcomes, including clinical T stage, histologic grade, clinical N stage, clinical M stage, age, and gender

As the airways are a major therapeutic target in the treatment of CF, many drugs are delivered by inhalation by using nebulizers, pressurized metered dose inhalers (pMDIs) and dry powder inhalers (DPIs)

Multiple comparisons were performed using unidirectional ANOVA or bidirectional ANOVA followed by the Bonferroni post-test

Unlike traditional viral vector-based methods for genetic modification, CRISPR-Cas9 offers two critical safety advantages, including elimination of insertional mutagenesis risks and precise gene editing without dependence on double-strand breaks