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We administered saline plus vehicle (control) and RSL3 or 5-FU alone and in combination (i.e., 5-FU plus RSL3)

Neurodegenerative diseases Several neurodegenerative diseases (NDs), such as epilepsy, Alzheimers disease (AD), Parkinsons disease (PD), Huntingtons disease (HD), and amyotrophic lateral sclerosis (ALS), which feature chronic progressive damage to the nervous system, have been proven to be tightly connected with nutrient availability and dietary patterns

Any damage to its physical integrity constitutes the initiating event of pathological processes, with tight junctions and the basement membrane being the two primary targets of attack

p53 is required for radiation-induced apoptosis in mouse thymocytes